23) Maternal seafood consumption in pregnancy and Neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study

Hibbeln JR et al, Lancet. 2007 Feb 17; 369(9561):578-85.

Optimum fetal neurodevelopment is dependent on Specific nutrients derived solely from dietary sources, including docosahexaenoic acid (DHA), dietary DHA intake improves clinical outcomes and neuronal myelination.

Greater maternal intake of omega-3 fatty acids was associated with lower risk of suboptimum verbal IQ
in a non-linear dose-response curve that lower omega-3 fatty acid intake in pregnancy predict lower verbal IQ.Insufficient intakes of long chain omega-3 fatty acids during pregnancy include: intrauterine growth retardation, delayed or suboptimum depth perception, adverse neurodevelopmental measures, residual deficits in fine motor skills, speed of information processing in infants, and irreversible deficits in serotonin and dopamine release.

We noted that children of mothers who ate small amounts of seafood were more likely to have Suboptimum neurodevelopmental outcomes than children of mothers who ate more seafood than the recommended amounts.