DHA supplementation, early in pregnancy, may reduce the incidence of deep placentation disorders. DHA supplementation, early in pregnancy, will become a safe and effective strategy for primary prevention of highly relevant pregnancy diseases, such as preterm birth, preeclampsia, and fetal growth restriction.
Average birth weight significantly increased in women who received DHA. DHA supplementation reduced the risk of intrauterine growth restriction. DHA is more powerful in stimulating extravillous trophoblast vasculogenesis.
Deep placentation disorders are the main outcome perhaps clinically modifiable with DHA supplementation early in pregnancy.
The more early in pregnancy DHA starts, the greater the effect on improving placentation is, making it possible to achieve a significant improvement in clinical outcomes.